|
KMID : 1377020120090050233
|
|
Tissue Engineering and Regenerative Medicine
2012 Volume.9 No. 5 p.233 ~ p.239
|
|
|
Perspective of bioartificial uterus as gynecological regenerative medicine
|
|
Huh Yul
Kim Yoon-Young
Ku Seung-Yup
|
|
|
Abstract
|
|
|
|
The fields of gynecology, organ transplantation, tissue engineering and regenerative medicine are in the process of convergence, promising the development of novel treatments for infertility highlighted by the advent of the bioartificial uterus. The advances made with in vitro fertilization, immunology, and stem cell biology have reopened dialogue regarding utilizing tissue engineering to create replacement reproductive organs for patients who do not have the ability to conceive naturally on their own. In this review, the possibility of creating a bioartificial uterus that can sustain gestation will be addressed with regards to the progenitor cells, various types of stem cells, the organ’s scaffolding and vasculature engineering, issues pertaining to the development of bioartificial uterus transplantation experimental model, as well as the long-term ethical implications that the bioartificial uterus poses for individuals and society as a whole.
|
|
|
KEYWORD
|
|
|
bioartificial uterus, endometrial stem cell, organ engineering, transplantation, uterine stem cell
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|
|